Status:

UNKNOWN

Total Thyroidectomy With Harmonic Scalpel®

Lead Sponsor:

Brazilian Society of Head and Neck Surgery

Collaborating Sponsors:

Johnson & Johnson

Conditions:

Thyroid Neoplasm

Goiter

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Harmonic scalpel is a new surgical instrument. Its use has been recommended in patients submitted to total thyroidectomy. Few randomized controlled trials has been published. However they had small sa...

Detailed Description

This is a multicentric open phase IV randomized controlled trial comparing patients submitted to total thyroidectomy comparing standard surgical procedure versus Harmonic scalpel assisted procedure. A...

Eligibility Criteria

Inclusion

  • Adult (\>18 y/o)
  • Benign or malignant thyroid disease
  • Proposal of total thyroidectomy
  • Normal thyroid function

Exclusion

  • Giant goiter
  • Hyperthyroidism
  • Non differentiated thyroid carcinoma
  • Locally invasive tumors
  • Neck dissection as a part of procedure
  • Previous surgery, radiotherapy or I131 therapy on neck
  • Video-assisted or endoscopic thyroidectomy
  • Severe comorbidities
  • Coagulation disorders

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

End Date :

Estimated Enrollment :

280 Patients enrolled

Trial Details

Trial ID

NCT00385983

Last Update

October 11 2006

Active Locations (9)

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Page 1 of 3 (9 locations)

1

Hospital Araujo Jorge

Goiânia, Goiás, Brazil

2

Hospital Erasto Gaertner

Curitiba, Paraná, Brazil

3

Instituto Nacional de Cancer INCA

Rio de Janeiro, Rio de Janeiro, Brazil

4

Hospital do Cancer de Natal

Natal, Rio Grande do Norte, Brazil