Status:

COMPLETED

Comparative Study of 0.5% Carboxymethylcellulose With 0.005% Stabilized Oxychlorocomplex (PURITE™) Versus 0.5% Carboxymethylcellulose in the Treatment of Dry Eye

Lead Sponsor:

Chulalongkorn University

Conditions:

Dry Eye Syndromes

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

To compare if 0.5% carboxymethylcellulose with 0.005% SOC (Stabilized oxychloro complex) have the same effectiveness and safety as 0.5% carboxymethylcellulose on dry eye patients.

Detailed Description

Dry eye is the very common disorder of tear film. There are millions of people who have dry eye around the world. Dry eye patients may suffer from redness, sandy sensation, itching, excessive watering...

Eligibility Criteria

Inclusion

  • Out patients of Ophthalmology department, King Chulalongkorn Memorial Hospital, who have symptoms and/or signs of dry eye
  • Bilateral dry eye symptoms and/or signs with equal severity between both eyes
  • Age \> 18 years, capable of following the study protocol, and considered be able to return for all scheduled visit

Exclusion

  • Different severity of dryness between both eyes
  • Current or recent use of topical ophthalmic medications that could affect dry eye condition
  • History of any systemic or ocular disorder or condition that could possibly interfere with the interpretation of study result
  • Recent contact lens wear (within one month)
  • Known hypersensitivity to 0.005% SOC or carboxymethylcellulose
  • Pregnancy or planned pregnancy
  • Having received permanent punctal occlusion

Key Trial Info

Start Date :

February 1 2004

Trial Type :

INTERVENTIONAL

End Date :

October 1 2005

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00386646

Start Date

February 1 2004

End Date

October 1 2005

Last Update

June 3 2015

Active Locations (1)

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Chulalongkorn Hospital

Bangkok, Bangkok, Thailand, 10330