Status:
COMPLETED
Outcome Following Antidepressant Treatment on Possible Endo-Phenotypes for Major Depression
Lead Sponsor:
University of Copenhagen
Conditions:
Healthy
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether outcome following antidepressant treatment can be used as a tool to evaluate endo-phenotypes for depression.
Detailed Description
The research in depression has for some years focused at the identification of endo-phenotypes. Endo-phenotypes are heritable biological or psychological markers, which are more commonly found in pati...
Eligibility Criteria
Inclusion
- Offsprings or siblings of patients with major depression
- Born in Denmark with European parents and grandparents
- For women; not pregnant or breastfeeding
- Written informed consent
Exclusion
- Somatically illness or other handicaps which make participation in the study impossible
- Daily intake of drugs interfering with corticosteroids or escitalopram
- Hypersensitivity to escitalopram, dexamethasone or human corticotropin-releasing hormone
- Former medical or psychological treatment for diseases in the affective or schizophrenic spectrum
- Ongoing addiction of alcohol or psychoactive drugs
Key Trial Info
Start Date :
April 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2009
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00386841
Start Date
April 1 2007
End Date
June 1 2009
Last Update
June 30 2009
Active Locations (1)
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1
Psychiatric Department of Rigshospitalet
Blegdamsvej 9, Copenhagen OE, Denmark, 2100