Status:

COMPLETED

Sentinel Lymph Node (SLN) Biopsy for Conjunctival/Eyelid Melanoma

Lead Sponsor:

M.D. Anderson Cancer Center

Conditions:

Eye Disease

Melanoma

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

The goal of this clinical research study is to find the sentinel lymph node (SLN) (s) and biopsy it (them) to see if the patient has small or low volume metastatic disease that would otherwise have be...

Detailed Description

You have had your conjunctival or eyelid tumor surgically removed or it is scheduled to have it removed. You will have lymphatic mapping before the tumor is removed. Lymphatic mapping is when a small ...

Eligibility Criteria

Inclusion

  • Participants must be 18 years of age or older.
  • Histologically documented malignant melanoma of the conjunctiva/eyelid greater than or equal to 1 millimeter in thickness, or those less than 1 mm thick that have evidence of ulceration, mitotic figures or are Clark IV.
  • A CXR, liver enzymes, and a head and neck computed tomography (CT) or magnetic resonance imaging (MRI) negative for evidence of metastasis.
  • Participant must have a negative ultrasound of regional lymph nodes (i.e., within 6 weeks of study enrollment).
  • Patient provided written informed consent. In the event that non-English speaking participants are eligible for this study, a short form (if applicable) or an ICD in their language, will be utilized and completed in accordance with the MDACC Policy for Consenting Non-English Speaking Participants.

Exclusion

  • 1\) Pregnant or nursing females.

Key Trial Info

Start Date :

May 30 2000

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 28 2023

Estimated Enrollment :

38 Patients enrolled

Trial Details

Trial ID

NCT00386906

Start Date

May 30 2000

End Date

September 28 2023

Last Update

May 7 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Texas MD Anderson Cancer Center

Houston, Texas, United States, 77030