Status:
COMPLETED
Effects of L-Carnitine on Postprandial Clearance of Triglyceride-rich Lipoproteins in HIV Patients on HAART
Lead Sponsor:
University of California, Davis
Conditions:
Hyperlipidemia
HIV Infections
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Included in this study will be patients with HIV and being treated with highly active antiretroviral medications (HAART) including protease inhibitors (PI) or non-nucleoside reverse transcriptase inhi...
Detailed Description
The postprandial state is a proinflammatory and proatherogenic condition. Increasing evidence support the contention the elevated triglyceride (TG)-rich lipoproteins (TGRL) are atherogenic. Hypertrigl...
Eligibility Criteria
Inclusion
- Men and Women Ages 18-70,
- Stable HAART regimen x 6 mo,
- PI or NNRTI based regimens,
- Caucasian, African American or Hispanic patients
Exclusion
- Diabetes Mellitus,
- Liver Disease,uncontrolled
- Pregnant or nursing mothers,
- BMI\> 35,
- Hemoglobin \<11 g/dl,
- Conditions known to lower seizure threshold (ie. brain tumor) or taking medications that lower seizure threshold,
- Patients taking: Warfarin, ValproicAcid or Zidovudine,Wellbutrin or Effexor
- Chronic Kidney Disease Stage 3-5,
- Untreated Thyroid Disease,
- Hormone replacement therapy,
- Triglycerides \>500 mg/dl (fasting)
Key Trial Info
Start Date :
October 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2009
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT00386971
Start Date
October 1 2006
End Date
December 1 2009
Last Update
May 30 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
GCRC UC Davis
Sacramento, California, United States, 95817