Status:

COMPLETED

Effect of Prolonged Electrical Stimulation on Neural Plasticity in Spinal Cord Injury

Lead Sponsor:

VA Office of Research and Development

Conditions:

Spinal Cord Injury

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Electrical stimulation (pulses of electricity applied over the skin of your wrist) and activity-based hand exercise have been shown to improve motor skill and strength in individuals with stroke and h...

Detailed Description

Spinal cord injury (SCI) affects 10,000 individuals per year in the United States. Approximately one half of all individuals with SCI have tetraparesis due to cervical injury. Impaired hand function s...

Eligibility Criteria

Inclusion

  • Trace voluntary thumb movement or able to pick up small objects with a tenodesis grip
  • Between ages 18 and 60
  • Spastic paresis (manifest as spasms, clonus, and/or hyperreflexia) due to neurologically incomplete SCI
  • Medically stable
  • Communicate questions/needs and answer yes/no questions reliably.

Exclusion

  • Altered cognitive status
  • Level of injury caudal to the C7 level
  • History of CVA, seizures
  • Implanted metal devices in the head, less than one year post injury, and severe spasticity of the muscles of the upper extremities (defined by a score of 2 or higher on the Modified Ashworth Spasticity Scale)
  • Patients with pacemakers will also be excluded from this study.

Key Trial Info

Start Date :

October 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2011

Estimated Enrollment :

11 Patients enrolled

Trial Details

Trial ID

NCT00387673

Start Date

October 1 2006

End Date

June 1 2011

Last Update

June 16 2017

Active Locations (1)

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VA Medical Center, Miami

Miami, Florida, United States, 33125