Status:

COMPLETED

Safety and Effectiveness of Cardiac Resynchronization Therapy With Defibrillation

Lead Sponsor:

Boston Scientific Corporation

Conditions:

Heart Failure, Congestive

Ventricular Fibrillation

Eligibility:

All Genders

Phase:

PHASE2

PHASE3

Brief Summary

The purpose of this study was to determine if cardiac resynchronization therapy when combined with defibrillation is safe and effective in the treatment of symptomatic heart failure.

Detailed Description

Patients enrolled received a device with cardiac resynchronization therapy (CRT) and defibrillation. Patients were randomized to CRT on or off for up to six months and evaluated for mortality, hospita...

Eligibility Criteria

Inclusion

  • Symptomatic heart failure
  • Left ventricular ejection fraction \<= 35%
  • QRS width \>= 120 ms
  • Indicated for an implantable cardioverter defibrillator

Exclusion

  • Indicated for a pacemaker
  • Atrial tachyarrhythmias

Key Trial Info

Start Date :

February 1 1998

Trial Type :

INTERVENTIONAL

End Date :

August 1 2001

Estimated Enrollment :

581 Patients enrolled

Trial Details

Trial ID

NCT00387803

Start Date

February 1 1998

End Date

August 1 2001

Last Update

January 25 2007

Active Locations (1)

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1

Multiple locations

Saint Paul, Minnesota, United States, 55112