Status:

COMPLETED

Danish Aspirin Resistance Trial - Pilot Study

Lead Sponsor:

University of Aarhus

Collaborating Sponsors:

Danish Research Agency

Conditions:

Drug Resistance

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Despite treatment with aspirin a large number of patients suffer a myocardial infarction. It has been speculated that these patients might be "resistant" to aspirin, and studies have indicated that th...

Detailed Description

Platelets play a major role in arterial thrombus formation - the cause of cardiovascular death, acute myocardial infarction and ischemic stroke and the number one killer in the Western World. Binding ...

Eligibility Criteria

Inclusion

  • ischemic heart disease verified with a coronary angiogram
  • treatment with 75 mg aspirin once daily

Exclusion

  • ischemic vascular event within the previous 12 months
  • percutaneous coronary intervention or coronary artery by-pass grafting within the previous 12 months
  • treatment with NSAID, clopidogrel, ticlopidine, dipyridamole, warfarin or any other drug affecting platelet aggregation
  • platelet count \< 120 x 10\^9/l
  • not able to give informed consent

Key Trial Info

Start Date :

November 1 2006

Trial Type :

INTERVENTIONAL

End Date :

March 1 2007

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00389129

Start Date

November 1 2006

End Date

March 1 2007

Last Update

December 12 2007

Active Locations (1)

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Department of Cardiology, Skejby Sygehus, Aarhus University Hospital

Aarhus, Denmark, 8200