Status:

UNKNOWN

Adding a Second Drug for Febrile Children Treated With Acetaminophen

Lead Sponsor:

Assaf-Harofeh Medical Center

Conditions:

Fever

Eligibility:

All Genders

6-4 years

Phase:

NA

Brief Summary

Fever is one of the most common symptoms in pediatrics and one of the most common reasons for visits in pediatricians' office and pediatric emergency departments. Many parents consider fever to be the...

Detailed Description

Methods: Design: randomized double blind placebo controlled study. Setting: The ED and pediatric ward of a large University affiliated Hospital Participants: Inclusion criteria: * Age: 6 mo- 4 yea...

Eligibility Criteria

Inclusion

  • Age: 6 mo- 4 years
  • Rectal temperature \> 38.5
  • Received 10-15 mg/kg of acetaminophen or 5-10 mg/kg of ibuprofen 1.5 - 3.5 hours before admission to the

Exclusion

  • Received more than 75 mg acetaminophen in the last 24 hours
  • Unable to take oral medications
  • Hypersensitivity to acetaminophen or ibuprofen
  • Varicella
  • Renal failure
  • Liver disease
  • Rectal temperature can't be measured (due to anatomical or medical problem)
  • Received both Ibuprofen and acetaminophen in the last 6 hours
  • Informed consent could not be granted

Key Trial Info

Start Date :

September 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2008

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00389272

Start Date

September 1 2005

End Date

December 1 2008

Last Update

October 31 2007

Active Locations (1)

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Pediatric Emergency Medicine Service, Assaf Harofeh Medical Center

Ẕerifin, Israel, 70300