Status:

COMPLETED

Risperidone or Cognitive-Behavioral Therapy for Improving Medication Treatment for Obsessive-compulsive Disorder

Lead Sponsor:

New York State Psychiatric Institute

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

Obsessive-Compulsive Disorder

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

This study will compare the short- and long-term effectiveness of two common therapies in improving serotonin reuptake inhibitor treatment in people with obsessive-compulsive disorder.

Detailed Description

Obsessive-compulsive disorder (OCD) is a common psychiatric illness. People with OCD experience unwelcome thoughts, known as obsessions, and feel compelled to perform repetitive behaviors, or compulsi...

Eligibility Criteria

Inclusion

  • Primary diagnosis of OCD
  • Currently on a stable and adequate dose of an SRI
  • Sufficient severity of symptoms to warrant additional augmentation treatment

Exclusion

  • Medical or psychiatric conditions that would make participation in the study unsafe
  • Currently receiving psychotherapy elsewhere at the time of study entry
  • Previously (within 12 weeks prior to study entry) attended 8 or more sessions of EX/RP within a 2-month period or received at least 4 weeks of antipsychotic augmentation while on an adequate SRI dose
  • Currently being treated with an SRI for the first time and has not yet responded, but has not tried another SRI

Key Trial Info

Start Date :

October 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2012

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00389493

Start Date

October 1 2006

End Date

December 1 2012

Last Update

April 25 2014

Active Locations (2)

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Page 1 of 1 (2 locations)

1

New York State Psychiatric Institute

New York, New York, United States, 10032

2

University of Pennsylvania Center for the Treatment and Study of Anxiety

Philadelphia, Pennsylvania, United States, 19104