Status:

WITHDRAWN

Study of LJP 394 (Abetimus Sodium) in Lupus Patients

Lead Sponsor:

La Jolla Pharmaceutical Company

Conditions:

Systemic Lupus Erythematosus

Eligibility:

All Genders

12-70 years

Phase:

PHASE2

Brief Summary

The primary purpose of this study is to assess the safety and pharmacodynamic effect of LJP 394 at doses of 100 mg, 300 mg and 900 mg on anti-dsDNA antibody levels in patients with SLE.

Detailed Description

STUDY NOW INCORPORATED INTO PHASE 3 STUDY NCT00089804.

Eligibility Criteria

Inclusion

  • Males or females between 12 and 70 years old.
  • Diagnosis of Systemic Lupus Erythematosus (SLE)
  • Females must be non-pregnant and non-lactating. Females must agree to use adequate birth control methods during the course of the study.
  • Ability to have weekly intravenous (IV) administration of study drug.

Exclusion

  • Prior exposure to abetimus sodium within 6 months prior to screening.
  • Patients not on stable medications for 30 days prior to screening.
  • Patients with acute or chronic infections.

Key Trial Info

Start Date :

September 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00390091

Start Date

September 1 2006

Last Update

September 1 2015

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Wallace Rheumatic Study Center

Los Angeles, California, United States, 90048

2

Altoona Center for Clinical Research

Duncansville, Pennsylvania, United States, 16635