Status:
COMPLETED
Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery (0966-179)(COMPLETED)
Lead Sponsor:
Merck Sharp & Dohme LLC
Conditions:
Pain, Postoperative Arthroscopy
Eligibility:
All Genders
18-60 years
Phase:
PHASE3
Brief Summary
Study the effect of rofecoxib 50 mg compared to both placebo, and hydrocodone 7.5 mg with acetaminophen 750 mg, to treat moderate to severe pain following arthroscopic knee surgery.
Eligibility Criteria
Inclusion
- Elective outpatient arthroscopic knee surgery expected to last \<= 90 minutes using general anesthesia
- Patients must experience moderate to severe pain following surgery
- Patient must be in general good health as judged by the primary investigator
Exclusion
- Osteoarthritis; rheumatoid arthritis
- Allergy/sensitivity to aspirin, ibuprofen, indomethacin, other NSAIDs, COX-2 inhibitors (e.g., rofecoxib, celecoxib), hydrocodone, acetaminophen
- Asthma associated with nasal polyps
- Any arthroscopic knee surgery in the past 6 months
Key Trial Info
Start Date :
February 1 2002
Trial Type :
INTERVENTIONAL
End Date :
February 1 2003
Estimated Enrollment :
420 Patients enrolled
Trial Details
Trial ID
NCT00390260
Start Date
February 1 2002
End Date
February 1 2003
Last Update
February 2 2017
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