Status:

COMPLETED

Short Course Nitrofurantoin for Acute Cystitis

Lead Sponsor:

University of Washington

Collaborating Sponsors:

Procter and Gamble

Conditions:

Urinary Tract Infection

Eligibility:

FEMALE

18-45 years

Phase:

PHASE2

Brief Summary

The purpose of this research study is to determine what the cure rates are with a 5 day course of nitrofurantoin versus the more standard 3 day course of trimethoprim/sulfamethoxazone. The study will ...

Detailed Description

The purpose of this research study is to determine what the cure rates are with a 5 day course of nitrofurantoin versus the more standard 3 day course of trimethoprim/sulfamethoxazone. The study will ...

Eligibility Criteria

Inclusion

  • Women 18-45 years of age who were nonpregnant, in good general health, and had symptoms of acute cystitis (dysuria) and a urine culture with ³102 cfu/ml of a uropathogen

Exclusion

  • Women who were pregnant, lactating, or not regularly contracepting or with diabetes, had known anatomic abnormalities of the urinary tract, allergy to any of the study drugs, recent (\<2 weeks) exposure to an oral or parenteral antimicrobial, or who were currently using prophylactic antibiotics were not eligible

Key Trial Info

Start Date :

January 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2005

Estimated Enrollment :

338 Patients enrolled

Trial Details

Trial ID

NCT00391651

Start Date

January 1 2002

End Date

July 1 2005

Last Update

June 5 2014

Active Locations (1)

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1

University of WA

Seattle, Washington, United States, 98195