Status:

COMPLETED

Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial)

Lead Sponsor:

Alfasigma S.p.A.

Collaborating Sponsors:

Theravance Biopharma

Conditions:

Chronic Constipation

Eligibility:

All Genders

18-64 years

Phase:

PHASE2

Brief Summary

Study 0038 compares the safety and effectiveness of an investigational drug, TD-5108 with placebo (a sugar pill) for the treatment of chronic constipation.

Eligibility Criteria

Inclusion

  • Meet ROME III Criteria

Exclusion

  • Constipation caused by:colonic etiology, pelvic floor dysfunction, metabolic disturbances, neurologic disturbances,concomitant medications affecting bowel function
  • Chronic treatment with anticholinergics, narcotic analgesics
  • Irritable Bowel Syndrome

Key Trial Info

Start Date :

October 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2007

Estimated Enrollment :

360 Patients enrolled

Trial Details

Trial ID

NCT00391820

Start Date

October 1 2006

End Date

May 1 2007

Last Update

July 8 2025

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

Breco Research

Houston, Texas, United States, 77024

Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial) | DecenTrialz