Status:
COMPLETED
Penetrance of Third Generation Fluoroquinolones in Eyes With Functioning Filtering Blebs
Lead Sponsor:
Indiana University School of Medicine
Conditions:
Cataract
Eligibility:
All Genders
Phase:
PHASE4
Brief Summary
Based on previous results with eyes without filtering blebs, the aqueous concentrations of ofloxacin and levofloxacin will exceed the concentration of ciprofloxacin after either topical or topical plu...
Detailed Description
The purpose of this study is to assay human aqueous for concentrations of ofloxacin, ciprofloxacin and levofloxacin after topical or combined topical and oral administration in eyes with filtering ble...
Eligibility Criteria
Inclusion
- All patients with functioning filtering blebs will be evaluated prospectively for inclusion
Exclusion
- Any subject who is already scheduled to have cataract surgery performed will qualify for participation with the exception of the following exclusion criteria:
- Ongoing ocular inflammatory disease
- Bleb leakage - determined by Seidel test
- Suspected infection
- Known contraindications to use of any of these study medications.
- Pregnancy
Key Trial Info
Start Date :
November 1 2002
Trial Type :
INTERVENTIONAL
End Date :
May 1 2006
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT00392275
Start Date
November 1 2002
End Date
May 1 2006
Last Update
April 10 2013
Active Locations (3)
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1
Indiana University Hospital
Indianapolis, Indiana, United States, 46202
2
Richard L Rodeboush VA Medical Center
Indianapolis, Indiana, United States, 46202
3
Wishard Memorial Hospital
Indianapolis, Indiana, United States, 46202