Status:
UNKNOWN
Prevention of Contrast Induced Nephropathy With Sodium Bicarbonate
Lead Sponsor:
Norton Community Hospital
Conditions:
Contrast Induced Nephropathy
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
This will be a randomized controlled trial closely following the original protocol in the previous study published in JAMA 2004 by Merten et al. Patients will be randomly assigned to one of two treatm...
Detailed Description
Inclusion Criteria: * Stage III Chronic Kidney Disease (GFR 30-60ml/min per 1.73m2 calculated by using MDRD equation) * Inpatients at Norton Community Hospital scheduled to undergo diagnostic CT Scan...
Eligibility Criteria
Inclusion
- Stage III Chronic Kidney Disease (GFR 30-60ml/min per 1.73m2 calculated by using MDRD equation)
- Inpatients at Norton Community Hospital scheduled to undergo diagnostic CT Scan using contrast between the hours of 7am and 6pm
- 18+ years of age
Exclusion
- Exclusion Criteria
- Current clinical diagnosis of exacerbated congestive heart failure
- Creatinine \>8 mg/dL
- Change in serum Cre of at least 0.5mg/dL during previous 24hours
- Pre-existing dialysis patient
- Multiple myeloma
- Uncontrolled hypertension (definition: treated SBP \>160mmHg or DBP \>100mmHg
- Exposure to contrast 48 hours prior to study
- Allergy to contrast dye
- Pregnancy
- Patient has received pressor agents, fendolapam, mannitol, or mucomyst at time of study
- Acute myocardial infarction
Key Trial Info
Start Date :
November 1 2006
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
656 Patients enrolled
Trial Details
Trial ID
NCT00392405
Start Date
November 1 2006
Last Update
October 26 2006
Active Locations (1)
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1
Norton Community Hospital
Norton, Virginia, United States, 24273