Status:
COMPLETED
Fundus Autofluorescence Imaging in Age-related Macular Degeneration Using Confocal Scanning Laser Ophthalmoscopy
Lead Sponsor:
University Hospital, Bonn
Conditions:
Age-related Macular Degeneration
Eligibility:
All Genders
50+ years
Brief Summary
The purpose of this study is to define phenotypic variations in atrophic Age-Related Macular Degeneration (AMD) and to identify predictive factors for disease progression based on fundus autofluoresce...
Detailed Description
Age-related macular degeneration (AMD) is the leading cause of legal blindness in the industrialized world beyond 50 years of age. Ageing changes of the retinal pigment epithelium (RPE) play a key rol...
Eligibility Criteria
Inclusion
- Must be considered reliable, willing and able to give informed consent.
- Age \>50 years (male or female)
- Must have age-related macular degeneration in at least one eye
- Clear media to allow imaging
Exclusion
- any history of retinal surgery, including laser treatment, photodynamic therapy, radiation or intravitreal injections
- history of retinal vascular occlusions
- any concurrent intraocular condition that, in the opinion of the investigator, could exclude the patient from the medical or ethical point of view
Key Trial Info
Start Date :
August 1 2000
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2018
Estimated Enrollment :
700 Patients enrolled
Trial Details
Trial ID
NCT00393692
Start Date
August 1 2000
End Date
October 1 2018
Last Update
October 11 2018
Active Locations (7)
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1
Department of Ophthalmology, University of Aachen
Aachen, Germany, 52074
2
Department of Ophthalmology, University of Heidelberg
Heidelberg, Germany, 69120
3
Institute for Medical Statistics and Biometry, University of Heidelberg
Heidelberg, Germany, 69120
4
Department of Ophthalmology, University of Leipzig
Leipzig, Germany, 04103