Status:

COMPLETED

A Study To Investigate GW427353 In Subjects With Irritable Bowel Syndrome (IBS)

Lead Sponsor:

GlaxoSmithKline

Conditions:

Irritable Bowel Syndrome (IBS)

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

This study will test the hypothesis that GW427353, a beta-3 adrenergic agonist, will relieve IBS pain or discomfort and associated symptoms in IBS patients.

Eligibility Criteria

Inclusion

  • \- Diagnosis of IBS which meets the Rome II criteria, screening pain score to be \> 1.5 (0= no pain, 4 = very severe pain)

Exclusion

  • Subjects not meeting the Rome II criteria for the diagnosis of IBS
  • Subjects with no stool for 7 days during the screen

Key Trial Info

Start Date :

August 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00394186

Start Date

August 1 2006

Last Update

May 18 2009

Active Locations (19)

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Page 1 of 5 (19 locations)

1

GSK Investigational Site

Concord, New South Wales, Australia, 2139

2

GSK Investigational Site

Caboolture, Queensland, Australia, 4510

3

GSK Investigational Site

Kippa-Ring, Queensland, Australia, 4021

4

GSK Investigational Site

Spring Hill, Queensland, Australia, 4000

A Study To Investigate GW427353 In Subjects With Irritable Bowel Syndrome (IBS) | DecenTrialz