Status:
UNKNOWN
Effect of Intraoperative Aprotinin Administration on Post Cardiac Surgery Optic Nerve and Retinal Thickness.
Lead Sponsor:
Soroka University Medical Center
Conditions:
Cardiac Surgery
Eligibility:
All Genders
Phase:
NA
Brief Summary
Cognitive and neurological dysfunction after coronary artery bypass surgery (CABG) is common and multi-factorial in origin. Several previous studies have shown that intraoperative aprotinin administra...
Detailed Description
Cognitive and neurological dysfunction after coronary artery bypass surgery (CABG) is common and multi-factorial in origin. Causative factors include cerebral Embolization (1), cerebral ischemia reper...
Eligibility Criteria
Inclusion
- patients admited for coronary artery bypass surgery
Exclusion
- Preoperative:
- Patients requiring concomitant noncoronary procedures.
- Urgent operation.
- Intra aortic balloon pump
- Presence of allergy to aprotinin or bleeding diathesis.
- Previous CVA.
- Previous eye operation.
- Glaucoma.
- Retinopathy.
- Postoperative:
- Postoperative CVA.
- Postoperative critical condition precluding safe performance of OCT examination.
Key Trial Info
Start Date :
December 1 2007
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00395369
Start Date
December 1 2007
Last Update
November 3 2006
Active Locations (1)
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1
Soroka Medical Center
Beersheba, Israel, 84101