Status:

COMPLETED

REPLACE: Implantable Cardiac Pulse Generator Replacement Registry

Lead Sponsor:

Biotronik, Inc.

Conditions:

Device Replacement

Elective Replacement (ERI)

Eligibility:

All Genders

18+ years

Brief Summary

The objective of this study is to prospectively estimate the all-cause complication rates at 6-months for patients undergoing generator replacement due to elective replacement indicator (ERI), advisor...

Detailed Description

Device replacements occur for many reasons, including elective replacement indication (ERI), manufacturer advisory, and upgrade. Recently pacemaker and implantable cardioverter (ICD) advisories have ...

Eligibility Criteria

Inclusion

  • Is able to give informed consent
  • Is identified for generator replacement without system modification or generator replacement including planned system modification, regardless of generator manufacturer
  • Is clinically stable to tolerate the surgical procedure
  • Age 18 years or greater
  • Is geographically stable and able to return to the investigational site for follow-up care through the six-month visit

Exclusion

  • Inability or unwillingness to give informed consent
  • Current system infection requiring generator explantation or lead extraction
  • Generator replacement requiring planned lead extraction
  • Participating in another cardiovascular investigational drug or device registry
  • A life expectancy of less than six months
  • Expected to receive a heart transplant within 6 months
  • All vulnerable subjects as defined by the FDA Office of Human Research Protection or the local IRB providing oversight

Key Trial Info

Start Date :

July 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2009

Estimated Enrollment :

1744 Patients enrolled

Trial Details

Trial ID

NCT00395447

Start Date

July 1 2007

End Date

June 1 2009

Last Update

April 14 2015

Active Locations (71)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 18 (71 locations)

1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35294

2

Mesa Cardiovascular

Mesa, Arizona, United States, 85206

3

Stanislaus Cardiology

Modesto, California, United States, 95355

4

Desert Cardiology

Rancho Mirage, California, United States, 92270