Status:

TERMINATED

Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting

Lead Sponsor:

Kensey Nash Corporation

Conditions:

Carotid Stenosis

Eligibility:

All Genders

18+ years

Phase:

PHASE2

PHASE3

Brief Summary

The purpose of this study is to evaluate the safety and efficacy of the TriActiv® ProGuard™ System when used during a stent placement in a blockage within the carotid artery in patients considered to ...

Detailed Description

Patients with certain anatomic or medical conditions have a greater risk of serious complications following carotid endarterectomy (a surgical procedure that removes blockages in the carotid artery). ...

Eligibility Criteria

Inclusion

  • Greater than 18 year of age
  • Patient gives informed consent
  • Less than 30mm stenosis in the common and/or internal carotid artery: at least a 50% stenosis if symptomatic or at least an 80% stenosis if asymptomatic
  • At least one medical or anatomic condition which makes the patient a high surgical risk.

Exclusion

  • Stroke within 14 days
  • Major stroke with significant residual effects
  • Myocardial infarction within 72 hours
  • Extensive atherosclerotic disease in the aortic arch or proximal common carotid artery
  • Severe carotid artery tortuosity
  • Total occlusion
  • Presence of thrombus or heavy calcification in the carotid artery
  • Pre-existing carotid artery dissection
  • Any planned interventional or surgical procedures within 30 days
  • Atrial fibrillation
  • Creatinine \> 2 mg/dL
  • Current participation in another investigational drug or device study

Key Trial Info

Start Date :

November 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2007

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT00395785

Start Date

November 1 2006

End Date

June 1 2007

Last Update

July 25 2007

Active Locations (34)

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Page 1 of 9 (34 locations)

1

University of Alabama Birmingham

Birmingham, Alabama, United States, 35294-0012

2

Thomas Hospital

Fairhope, Alabama, United States, 36532

3

Brotman Medical Center

Beverly Hills, California, United States, 90210

4

Good Samaritan Hospital

Los Angeles, California, United States, 90017