Status:
COMPLETED
Chronic and Acute Effects of Smoking on the Left and Right Ventricular Relaxation in Young Healthy Smokers
Lead Sponsor:
Medical University of Warsaw
Conditions:
Cardiovascular Diseases
Eligibility:
All Genders
18-40 years
Brief Summary
Impairment of relaxation, the early phase of ventricular diastole is the first stage of heart diastolic dysfunction. Left ventricular diastolic function can be determined noninvasively by Echo- Dopple...
Detailed Description
Echocardiographic examination: in left lateral position after 10 minutes rest. The first examination: after a 2-hour non-smoking period, the second: immediately after smoking one cigarette containing ...
Eligibility Criteria
Inclusion
- Smokers smoking over 10 cigarettes per day over the last 5 years
- Body mass index \< 25 kg/m2
- Normal blood pressure and normal parameters of echocardiographic examination (wall thickness, left- and right- chamber size, valvular function and left and right ventricular systolic function)
- Normal results of routine physical examination, chest x-ray, standard rest electrocardiogram and routine laboratory tests.
Exclusion
- Body mass index \> 25 kg/m2
- Abnormal blood pressure
- Abnormal parameters of echocardiographic examination (wall thickness, left- and right- chamber size, valvular function and left and right ventricular systolic function)
- Abnormal results of routine physical examination, chest x-ray, standard rest electrocardiogram and routine laboratory tests.
Key Trial Info
Start Date :
November 1 2001
Trial Type :
OBSERVATIONAL
End Date :
November 1 2004
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT00395928
Start Date
November 1 2001
End Date
November 1 2004
Last Update
November 6 2006
Active Locations (1)
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1
Internal Medicine and Cardiology Dpt,Institute of Dentistry,Warsaw Medical University
Warsaw, Lindleya 4, Poland, 02 005