Status:

COMPLETED

Comparison of the Safety and Efficacy of Intravenous Iron Versus Oral Iron in the Treatment of Anemia Secondary to Heavy Uterine Bleeding

Lead Sponsor:

American Regent, Inc.

Conditions:

Anemia

Eligibility:

FEMALE

18+ years

Phase:

PHASE3

Brief Summary

This study compares of the safety and efficacy of intravenous iron vs oral iron in the treatment of anemia secondary to heavy uterine bleeding

Detailed Description

This is an open-label, randomized, Phase III, active-control, study of the efficacy and safety of IV iron vs oral iron in patients with anemia secondary to heavy uterine bleeding.

Eligibility Criteria

Inclusion

  • Female subjects \>/= 18 years of age
  • History of Heavy uterine bleeding
  • Hgb \</= 11
  • Practicing acceptable birth control
  • Demonstrate ability to understand and comply with protocol

Exclusion

  • Known Hypersensitivity to oral or IV iron
  • Anemia other than iron deficiency anemia
  • Iron storage disorders
  • Initiation of treatment that may effect degree of heavy uterine bleeding
  • Anticipated need for surgery
  • Severe psychiatric disorder
  • Active infection
  • Positive Pregnancy test
  • Known Hep B or C or Active Hepatitis
  • Received investigational Drug within 30 days
  • Alcohol or drug abuse

Key Trial Info

Start Date :

May 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2006

Estimated Enrollment :

456 Patients enrolled

Trial Details

Trial ID

NCT00395993

Start Date

May 1 2005

End Date

June 1 2006

Last Update

February 20 2018

Active Locations (1)

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1

Luitpold Pharmaceuticals, Inc.

Norristown, Pennsylvania, United States, 19403