Status:
UNKNOWN
A Brain Imaging Study Into Nicotine Induced Dopamine Release in Cigarette Smokers.
Lead Sponsor:
Hadassah Medical Organization
Conditions:
Tobacco Use Disorder
Eligibility:
MALE
21-50 years
Phase:
NA
Brief Summary
Dopamine (DA) plays a critical role in nicotine (and other) addiction and this drug is known to release DA in brain areas mediating reward and motivational processes. Although imaging studies show tha...
Detailed Description
Dopamine plays a critical role in nicotine(and other) addiction and this drug is known to release DA in brain areas mediating reward and motivational processes. Although imaging studies show that rele...
Eligibility Criteria
Inclusion
- smokers who smoked 15 cigarettes/day and who met the DSM-IV criteria for nicotine dependence
Exclusion
- Subjects who are diagnosed as suffering from psychotic illness according to DSM-IV (Axis 1)22, or with a history of CNS disease, a history of infection that might affect CNS (HIV, syphilis, cytomegalovirus, herpes), or a history of head injury with loss of consciousness will be excluded.
Key Trial Info
Start Date :
July 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2012
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00396669
Start Date
July 1 2007
End Date
July 1 2012
Last Update
March 27 2012
Active Locations (1)
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1
Hadassah Medical Organization
Jerusalem, Israel, 91120