Status:
COMPLETED
A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes
Lead Sponsor:
Incyte Corporation
Conditions:
Insulin Resistance
Obesity
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to determine whether the investigational drug INCB013739 has an effect on systemic and adipose tissue 11-HSD1 activity in obese, insulin resistant subjects.
Detailed Description
"Proprietary Information: Exploratory (Non-Confirmatory) Trial".
Eligibility Criteria
Inclusion
- Male and female subjects between 18 years and 65 years of age.
- BMI between 30 and 42 kg/m2, inclusive.
- FPG \<126 mg/dL
Exclusion
- Meet criteria for diagnosis of diabetes mellitus at the screening evaluation, female subjects with a history of gestational diabetes are permitted.
- Are receiving oral antidiabetic agents within the 3 months prior to screening.
Key Trial Info
Start Date :
November 1 2006
Trial Type :
INTERVENTIONAL
End Date :
March 1 2007
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00398619
Start Date
November 1 2006
End Date
March 1 2007
Last Update
January 23 2012
Active Locations (2)
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1
Beverly Hills, California, United States, 90211
2
Chula Vista, California, United States, 91911