Status:

COMPLETED

Cediranib (AZD2171, RECENTIN™) in Addition to Chemotherapy in Patients With Untreated Metastatic Colorectal Cancer

Lead Sponsor:

AstraZeneca

Conditions:

Metastatic Colorectal Cancer

Eligibility:

All Genders

18-130 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to determine if Cediranib when added to chemotherapy is more effective than chemotherapy alone in prolonging life expectancy and slowing disease progression in patients wi...

Eligibility Criteria

Inclusion

  • Written Informed Consent
  • Carcinoma of the colon or rectum
  • One or more measurable lesions

Exclusion

  • Adjuvant/neoadjuvant therapy within 6-12 months of study entry
  • Untreated unstable brain or meningeal metastases
  • Specific laboratory ranges
  • Specific cardiovascular problems
  • Participation in other trials within 30 days

Key Trial Info

Start Date :

November 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2016

Estimated Enrollment :

1254 Patients enrolled

Trial Details

Trial ID

NCT00399035

Start Date

November 1 2006

End Date

August 1 2016

Last Update

December 28 2016

Active Locations (90)

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Page 1 of 23 (90 locations)

1

Research Site

Buenos Aires, Argentina

2

Research Site

Capital Federal, Argentina

3

Research Site

Ciudad de Buenos Aires, Argentina

4

Research Site

Córdoba, Argentina