Status:

COMPLETED

Oral Androgens in Man-4: (Short Title: Oral T-4)

Lead Sponsor:

University of Washington

Collaborating Sponsors:

GlaxoSmithKline

Conditions:

Contraception

Eligibility:

MALE

18-55 years

Phase:

PHASE1

PHASE2

Brief Summary

The protocol was designed to address the hypothesis that oral testosterone enanthate plus dutasteride can suppress the secretion of LH and FSH after four weeks of administration. In addition, we will ...

Detailed Description

This study will be carried out in a double-blinded fashion, so neither the subject nor the investigator will be aware of treatment assignment during the study. This protocol is designed to address the...

Eligibility Criteria

Inclusion

  • Males between 18 to 55 years of age
  • In good general health based on normal screening evaluation (consisting of a medical history, physical exam, normal serum chemistry, hematology, and baseline hormone levels)
  • Subject must agree not to participate in another research drug study for the duration of the study
  • Subject must agree to not donate blood during the study
  • Subject must be willing to comply with the study protocol and procedures

Exclusion

  • Men in poor general health, with abnormal blood results (clinical laboratory tests or hormone values)
  • A known history of alcohol or drug abuse
  • A history of testicular disease or severe testicular trauma,
  • A history of bleeding disorders or current use of anti-coagulants
  • A history of sleep apnea and/or major psychiatric disorders
  • A body-mass index greater than 35,
  • A history of or current use of testosterone
  • Infertility

Key Trial Info

Start Date :

November 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2007

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00399165

Start Date

November 1 2006

End Date

May 1 2007

Last Update

September 22 2008

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Washington

Seattle, Washington, United States, 98195