Status:

TERMINATED

Evaluation Of The Efficacy and Safety Of Tri-ActiveTM In Treatment Of Cellulite

Lead Sponsor:

Hexsel Dermatology Clinic

Conditions:

Cellulite

Body Contouring

Eligibility:

FEMALE

18-45 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to assess the efficacy of device TRI-ACTIVETM (DEKA M.E.L.A., Itália)in the treatment od cellulite and body contouring.

Detailed Description

The present study is a clinical, opened trial and single-center. The patients will be treated by six laser diodes, localised cooling system and rhythmical intake massage device. Application of the ma...

Eligibility Criteria

Inclusion

  • Written Informed Consent;
  • Subjects agreeing to take part of all procedures of the study (including mechanical massage, photographs), after being fully informed on the objectives and nature of the investigations;
  • Female subjects between 18-45 years;
  • Subjects presenting with cellulite grades I-III on buttocks and thighs;
  • Medical history and physical examination which, based on the investigator's opinion, do not prevent the patient from taking part in the study and use the device under investigation;
  • Female subjects of childbearing age should present a negative urine pregnancy test and should be using an effective contraceptive method (3 months before the enrollement untill the end of the study);
  • Body Mass Index (BMI = weight/height2) beetwen 20,0-25,0;
  • Availability of the subject throughout the duration of the study (60 days);
  • Availability of the subject in maintaining a stable weight during the study (variation less than 2 kg)
  • Subjects with sufficient schooling and awareness to enable them to cooperate to the degree required by this protocol.

Exclusion

  • Pregnant women or women intending to become pregnant during the study (next 3 months);
  • BMI superior 25,0;
  • Subjects with diabetes mellitus, cardiac insufficiency, asthma, or bronchitis;
  • Subjects participating in other clinical trials;
  • Subjects with neoplastic disorders, uncontrolled thyroid disorders or uncontrolled hypertension;
  • Subjects with coagulation disorders, using anticoagulants or tendency of bruises;
  • Subjects with vascular disorders (phlebitis or varicose veins) in the area to be treated;
  • Any prior aesthetic surgery affecting the area to be treated (liposuction, Subcision®), 3 months before the study, that may interfere with results;
  • Any other prior anti-cellulite treatment or body measures treatment, 30 days prior to the study;
  • Subjects with inflammation or active infection in the area to be treated.
  • Subjects with a history of adverse effects, which in the investigator's opinion should prevent the patient from participating in the study;
  • Patients with cutaneous or vascular alterations, that difficult visualization and documentation of cellulite;
  • Subjects with a history of medical treatment non-adherence or showing unwillingness to adhere to the study protocol;
  • Subjects who can not come to the visits (one missing visit/ month is allowed);
  • Subjects intending to initiate any intensive sport;
  • Subjects using analgesics, non-hormonal antiinflammatories, antihistaminics, corticosteroids, or diuretics;
  • Subjects tanned, or intending to expose the area of study to sun, artificial UV, or self-tanning during the study;
  • Any condition that, in the opinion of the investigator, can compromise the evaluation of the study.

Key Trial Info

Start Date :

August 1 2006

Trial Type :

INTERVENTIONAL

End Date :

November 1 2006

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00399828

Start Date

August 1 2006

End Date

November 1 2006

Last Update

March 12 2008

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