Status:
COMPLETED
Dietary Fish Protein in Subjects With Insulin Resistance
Lead Sponsor:
Laval University
Collaborating Sponsors:
Canadian Institutes of Health Research (CIHR)
Conditions:
Insulin Resistance
Type 2 Diabetes
Eligibility:
All Genders
35-65 years
Phase:
PHASE2
Brief Summary
The objective of our research project is to determine the effects of fish protein, present in fish, on insulin sensitivity in insulin-resistant human individuals, and its mechanism of action on glucos...
Detailed Description
Recent data show that cod protein prevents the development of insulin resistance in rats. Dietary fish protein may also enhance insulin sensitivity in overweight insulin-resistant subjects by improvin...
Eligibility Criteria
Inclusion
- overweight or obese (BMI between 25 and 40 kg /m2)
- waist circumference above 88 cm for women and 102 cm for men
- fasting plasma insulin above 90 pmol/L
- fasting plasma glucose below 7.0 mmol/L and 2-h plasma glucose below 11.1 mmol/L
Exclusion
- Individuals with diagnosed diabetes or any chronic, metabolic or acute disease
- Individuals who had a major surgery within the last 3 months
- Individuals who had a significant weight loss (±10%) within the last 6 months
- Individuals taking any medication known to affect lipid or glucose metabolism
- Subjects with dietary incompatibility with fish consumption (allergy, intolerance or dislike) and/or calcium supplementation
- Smokers
Key Trial Info
Start Date :
February 1 2004
Trial Type :
INTERVENTIONAL
End Date :
December 1 2005
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00400036
Start Date
February 1 2004
End Date
December 1 2005
Last Update
November 16 2006
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Laval University
Québec, Quebec, Canada, G1K 7P4