Status:
COMPLETED
Efficacy and Safety Study of Esomeprazole 20mg qd vs Ranitidine 150mg Bid in Patients With an NSAID-induced Gastric Ulcer
Lead Sponsor:
AstraZeneca
Conditions:
Gastric Ulcer
Eligibility:
All Genders
18-70 years
Phase:
PHASE3
Brief Summary
The purpose of this study is to assess the efficacy of esomeprazole 20 mg dosed once daily and ranitidine 150 mg dosed twice daily through 4 weeks of treatment for the healing of gastric ulcers in pat...
Eligibility Criteria
Inclusion
- Signed informed consent.
- A clinical diagnosis of a chronic condition that requires daily NSAID treatment for at least 2 months.
- Daily NSAID dose and type must have been stable for at least 2 weeks prior to the baseline endoscopy;orally;
Exclusion
- History of esophageal, gastric or duodenal surgery, except for simple closure of an ulcer.
- History of severe liver disease, including (but not limited to) cirrhosis and acute or chronic hepatitis.
Key Trial Info
Start Date :
March 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2008
Estimated Enrollment :
397 Patients enrolled
Trial Details
Trial ID
NCT00401752
Start Date
March 1 2006
End Date
November 1 2008
Last Update
July 8 2010
Active Locations (9)
Enter a location and click search to find clinical trials sorted by distance.
1
Research Site
Fuzhou, Fujian, China
2
Research Site
Guangzhou, Guangdong, China
3
Research Site
Wuhan, Hubei, China
4
Research Site
Suzhou, Jiangsu, China