Status:

COMPLETED

Comparison of Quantiferon-TB Gold Assay With Tuberculin Skin Testing in Patients With Chronic Liver Disease

Lead Sponsor:

University Health Network, Toronto

Conditions:

Chronic Liver Disease

Liver Transplantation

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of the study is to estimate the usefulness of the QuantiFERON®-TB Gold test for the diagnosis of latent tuberculosis infection in liver transplant candidates by correlating the test result...

Detailed Description

Tuberculosis (TB) is an important cause of morbidity and mortality in organ transplant recipients. Although the tuberculin skin test (TST) is recommended for screening of latent tuberculosis infection...

Eligibility Criteria

Inclusion

  • Chronic liver disease on the waiting list or being wait listed for liver transplantation

Exclusion

  • Unable to provide informed consent
  • Previous history of immediate hypersensitivity to TST
  • Previous severe local ulceration with TST
  • Suspected active TB

Key Trial Info

Start Date :

October 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2007

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT00402402

Start Date

October 1 2006

End Date

July 1 2007

Last Update

April 16 2008

Active Locations (1)

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1

Univcersity Health Network

Toronto, Ontario, Canada, M5G 2N2