Status:
COMPLETED
Randomized Trial of Immediate Versus Early and Selective Invasive Percutaneous Coronary Intervention in NSTEMI
Lead Sponsor:
University of Leipzig
Conditions:
Myocardial Infarction
Eligibility:
All Genders
18-89 years
Phase:
PHASE4
Brief Summary
In non-ST-elevation the optimal time of percutaneous coronary intervention (PCI) is unclear. Some studies showed benefit of very early PCI, some others early PCI between 12-48 hours and others even s...
Detailed Description
In this randomized, controlled, open-label clinical trial we compare a very early cardiac catheterization (\< 2,5 hours after randomization) similar to ST-elevation myocardial infarction treatment, ve...
Eligibility Criteria
Inclusion
- Clinical symptoms:
- Instable angina pectoris:
- Angina at rest \< 24 hours
- new onset worsening angina within the last weeks with angina at very low threshold \< 24 h
- Troponin T:
- Troponin T-elevation ≥ 0,03 μg/l
- Informed consent
Exclusion
- Age \< 18 years
- Age \> 90 years
- STEMI
- Hemodynamic instability
- Cardiogenic shock
- Warfarin therapy
- Contraindications for GpIIb/IIIa-inhibitors
- life expectancy \< 6 months
- known high bleeding risk
- Pregnancy
- Other reasons for Troponin-elevation: Myocarditis, secondary after hypertensive crisis, cardiac decompensation
- No informed consent
Key Trial Info
Start Date :
July 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2010
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT00402675
Start Date
July 1 2006
End Date
January 1 2010
Last Update
January 5 2010
Active Locations (5)
Enter a location and click search to find clinical trials sorted by distance.
1
Klinikum Links der Weser
Bremen, Germany, 28277
2
Städt. Klinikum St. Georg
Leipzig, Germany, 04129
3
University of Leipzig - Heart Center
Leipzig, Germany, 04289
4
University of Leipzig
Leipzig, Germany, 12103