Status:

COMPLETED

Safety/Efficacy of Zoledronic Acid and Alendronate on Bone Metabolism in Postmenopausal Women With Osteoporosis

Lead Sponsor:

Novartis

Conditions:

Osteoporosis

Eligibility:

FEMALE

55-90 years

Phase:

PHASE3

Brief Summary

The aim of this study was to examine the effect of zoledronic acid and alendronate on bone metabolism as measured by biomarkers in postmenopausal women with osteoporosis.

Eligibility Criteria

Inclusion

  • \- Low bone mineral density (as indicated by a "t-score" of -2.0 or lower) postmenopausal women

Exclusion

  • \- Previous use of oral and iv bisphosphonates, parathormone, strontium ranelate, sodium fluoride.
  • Other protocol-defined inclusion/exclusion criteria applied to the study.

Key Trial Info

Start Date :

October 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

604 Patients enrolled

Trial Details

Trial ID

NCT00404820

Start Date

October 1 2006

End Date

December 1 2008

Last Update

July 1 2011

Active Locations (1)

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Multiple Cities, Germany