Status:

RECRUITING

Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.

Lead Sponsor:

Syneos Health

Collaborating Sponsors:

AbbVie

Alvogen Inc.

Conditions:

HIV Infections

Hepatitis B

Eligibility:

FEMALE

12-60 years

Brief Summary

The purpose of the Antiretroviral Pregnancy Registry (Registry) is to detect any major teratogenic effect involving any of the Registry drugs when administered to pregnant people. Registration is volu...

Detailed Description

The following antiretroviral drugs are followed by the Antiretroviral Pregnancy Registry (APR, Registry) to detect any major teratogenic effect when administered to pregnant people: abacavir (ZIAGEN®,...

Eligibility Criteria

Inclusion

  • Eligibility Ages Eligible for Study: People of childbearing potential
  • Country of origin of report
  • Documentation that the registry drug was taken during pregnancy
  • Sufficient information to determine if the pregnancy is being prospectively or retrospectively registered
  • Date the pregnancy was registered
  • Source of report (patient or health care provider)
  • Whether the pregnancy outcome is already known or delivery is still pending
  • Timing of the prenatal exposure to the registry medication (no broader than which trimester)
  • Sufficient patient identifier relevant to reporter to allow for follow-up
  • Was patient involved in a study at the time of prenatal exposure
  • Full reporter contact information (name, address, etc.)

Exclusion

  • • People who were not exposed to registry medications during pregnancy

Key Trial Info

Start Date :

January 1 1989

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2099

Estimated Enrollment :

24258 Patients enrolled

Trial Details

Trial ID

NCT00404989

Start Date

January 1 1989

End Date

January 1 2099

Last Update

April 1 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Registry Coordinating Center

Wilmington, North Carolina, United States, 28403