Status:
WITHDRAWN
Validation of a Molecular Prognostic Test for Eye Melanoma
Lead Sponsor:
Washington University School of Medicine
Conditions:
Uveal Neoplasms
Choroid Neoplasms
Eligibility:
All Genders
Brief Summary
Up to half of patients with ocular melanoma (also called iris, choroidal or uveal melanoma) develop metastasis. We have found that certain molecular features of the eye tumor can be detected by gene e...
Detailed Description
We have discovered a gene expression profile derived from primary uveal melanomas that accurately predicts which patients will develop metastasis. Tumors with a class 1 gene expression signature have ...
Eligibility Criteria
Inclusion
- clinical diagnosis of melanoma of the iris, ciliary body and/or choroid
- treatment to include enucleation, radiotherapy or local tumor resection
Exclusion
- evidence of marked tumor necrosis
Key Trial Info
Start Date :
May 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00406120
Start Date
May 1 2007
End Date
May 1 2010
Last Update
June 26 2018
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110