Status:

COMPLETED

Neural Correlates of Lower Extremity Motor Recovery in Stroke Patients: Longitudinal Diffusion Spectrum Imaging Studies

Lead Sponsor:

National Taiwan University Hospital

Collaborating Sponsors:

National Science and Technology Council, Taiwan

Conditions:

Stroke

Eligibility:

All Genders

30-80 years

Brief Summary

To investigate the relationship between the integrity of the white matter, including the corticospinal tracts and the corpus callosum, with the recovery of lower extremity function in patients with ce...

Detailed Description

Recent studies have provided strong evidence that motor recovery after adult ischemic stroke is a function of neural plasticity. Up to date, it remains largely unknown as to the relationship between t...

Eligibility Criteria

Inclusion

  • between 30 to 80 years old
  • diagnosis of the first-time onset of stroke as confirmed by imaging studies
  • within 30 days post onset University Hospital
  • brain lesions mainly involving either the cortical primary motor cortex (M1) area or confined to the subcortical (M1 spared)
  • No neurological or orthopedic problems which would affect their lower extremity function
  • no contraindications for MRI studies

Exclusion

  • medically unstable
  • unable to communicate with the experimenters

Key Trial Info

Start Date :

August 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 1 2009

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT00407628

Start Date

August 1 2006

End Date

July 1 2009

Last Update

July 8 2013

Active Locations (1)

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Page 1 of 1 (1 locations)

1

School and Graduate Institute of Physical Therapy College of Medicine, National Taiwan University

Taipei, Taiwan, China

Neural Correlates of Lower Extremity Motor Recovery in Stroke Patients: Longitudinal Diffusion Spectrum Imaging Studies | DecenTrialz