Status:
COMPLETED
D-cycloserine for Major Depressive Disorder
Lead Sponsor:
Herzog Hospital
Collaborating Sponsors:
National Alliance for Research on Schizophrenia and Depression
Conditions:
Major Depressive Disorder
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
For many depression patients treatment changes are required, including switching to another antidepressant and addition of a second antidepressant or a non-antidepressant agent ("augmentation"). The n...
Eligibility Criteria
Inclusion
- DSM-IV diagnosis of major depression .
- HAMD scale score of ≥20 despite at least two adequate antidepressant treatment trials during the current episode.
Exclusion
- Underwent ECT treatment during the 3 months preceding the study.
- Change in psychotropic medications doses during the 3 weeks preceding the study.
- Concurrent unstable medical or neurological illness.
- Patients are judged to be potentially violent towards themselves or others, or have a history of drug/alcohol abuse.
Key Trial Info
Start Date :
January 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT00408031
Start Date
January 1 2007
End Date
May 1 2010
Last Update
August 3 2012
Active Locations (2)
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1
Ezrath Nashim - Herzog Memorial Hospital & Community Clinics
Jerusalem, Israel
2
Ezrath Nashim - Herzog Memorial Hospital
Jerusalem, Israel