Status:
TERMINATED
Ocular Pulse Amplitude And Choroidal Laser Doppler Flowmetry
Lead Sponsor:
University Hospital, Basel, Switzerland
Conditions:
Healthy
Eligibility:
All Genders
45-80 years
Brief Summary
This study intends to investigate the relationship between choroidal blood flow and ocular pulse amplitude (OPA).
Detailed Description
One eye is randomly selected in 18 healthy subjects. OPA is assessed with Dynamic Contour Tonometry. Submacular choroidal blood flow is measured with Laser Doppler Flowmetry. During both examinations ...
Eligibility Criteria
Inclusion
- Healthy subjects should present no history of ocular diseases, of current topical medication, or of drug or alcohol abuse. Furthermore, a best corrected visual acuity above 20/25 in both eyes, lack of pathological findings upon a slit-lamp examination and dilated direct fundoscopy, and an IOP \< 21 mmHg in both eyes will be required.
Exclusion
- History of chronic or recurrent severe inflammatory eye disease such as scleritis or uveitis.
- History of ocular trauma or intraocular surgery. History of infection or inflammation within the past 3 months.
- History and clinical evidence for other retinal disease such as age-related degeneration, or diabetic retinopathy.
Key Trial Info
Start Date :
January 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00409110
Start Date
January 1 2006
End Date
August 1 2011
Last Update
August 9 2011
Active Locations (1)
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1
University Eye Clinic Basel
Basel, Canton of Basel-City, Switzerland, 4031