Status:

UNKNOWN

Influence of Nutritional and Inflammational Status on Survival of Hemodialysis Patients

Lead Sponsor:

Assaf-Harofeh Medical Center

Conditions:

Inflammation

Body Composition

Eligibility:

All Genders

18+ years

Brief Summary

prospective longitudinal measurements of nutritional status parameters (body composition by BIA, anthropometry and biochemical indexes), inflammatory response (CRP, inflammatory cytokines (IL-1, IL-6,...

Eligibility Criteria

Inclusion

  • Male or female, age \> 18 years, in chronic hemodialysis treatment at least 3 months
  • Stable and adequate hemodialysis treatment three months prior to participation in study as defined by Kt/V \> 1.2 and/or hemodialysis performed 4 hours 3 times weekly
  • Patients with normal hydration status (edema-free), with no neuro-muscular diseases
  • Informed consent obtained before any trial-related activities

Exclusion

  • Patients with edema, pleural effusion or ascites at their initial assessment
  • Patients with active malignant disease or liver cirrhosis
  • Patients with neuro-muscular diseases
  • Patients on chronic treatment with steroids on doses \> 10 mg/day Prednisone (or equivalent)
  • Patients treated with immunosuppressive agents
  • Patients suffering from
  • Acute vasculitis
  • Severe systemic infections
  • Heart failure (NYHA class III-IV)
  • The receipt of any investigational drug within 1 month prior to initiating of this study

Key Trial Info

Start Date :

March 1 2006

Trial Type :

OBSERVATIONAL

End Date :

April 1 2008

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00410137

Start Date

March 1 2006

End Date

April 1 2008

Last Update

December 12 2006

Active Locations (1)

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Assaf-Harofeh Medical Center

Ẕerifin, Israel, 70300