Status:

COMPLETED

Pegfilgrastim Versus Filgrastim After High-dose Chemotherapy

Lead Sponsor:

Armando Santoro, MD

Conditions:

Hematological Neoplasms

Tumors

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The primary objective of the study is to evaluate the efficacy and the safety of pegfilgrastim versus filgrastim, administered after high-dose chemotherapy and peripheral stem cell reinfusion.

Detailed Description

Secondary objective is to evaluate the immunological reconstitution after pegfilgrastim and filgrastim.

Eligibility Criteria

Inclusion

  • Patients with hematological neoplasms or solid tumors candidable to high-dose chemotherapy with autologous peripheral stem cell reinfusion
  • Adequate organ function
  • Written informed consent.

Exclusion

  • Use of other experimental drugs
  • Active infection

Key Trial Info

Start Date :

September 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2008

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT00410696

Start Date

September 1 2006

End Date

November 1 2008

Last Update

July 1 2013

Active Locations (1)

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1

Istituto Clinico Humanitas

Rozzano, Milan, Italy, 20089