Status:
COMPLETED
Combined Vasopressin, Methylprednisolone, and Epinephrine for Inhospital Cardiac Arrest
Lead Sponsor:
University of Athens
Conditions:
Heart Arrest
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
A randomized controlled trial did not show benefit of vasopressin versus epinephrine in inhospital cardiac arrest. Preceding laboratory data suggest that combined vasopressin and epinephrine ensure lo...
Detailed Description
Inhospital cardiac arrest still constitutes an important clinical problem with survival to discharge ranging within 0-42% (most common range = 15-20%). Survival after witnessed, pulseless ventricular ...
Eligibility Criteria
Inclusion
- Adult in-patients with cardiac arrest requiring epinephrine according to current guidelines.
Exclusion
- Age \< 18 years.
- Documented terminal illness (life expectancy \< 6 weeks).
- Do not resuscitate status.
- Cardiac arrest before arrival at hospital.
- Prior enrollment into the study (i.e. second or third inhospital arrest etc.).
- Corticosteroid treatment before the cardiac arrest.
- Any inaccurate documentation of CPR data such as medication, number of countershocks etc.
Key Trial Info
Start Date :
June 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2007
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00411879
Start Date
June 1 2006
End Date
April 1 2007
Last Update
January 12 2016
Active Locations (1)
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1
Evaggelismos General Hospital
Athens, Attica, Greece, 106 75