Status:

COMPLETED

Pregabalin in the Treatment of Patients With Generalized Anxiety Disorder (GAD).

Lead Sponsor:

Pfizer's Upjohn has merged with Mylan to form Viatris Inc.

Conditions:

Generalized Anxiety Disorder

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The primary objective of this study is to evaluate the efficacy of pregabalin as compared to placebo in the treatment of patients with general anxiety disorder (GAD). Efficacy will be measured by the ...

Detailed Description

Further enrollment in this study was stopped on January 28, 2008 based on the recommendation of an independent data monitoring committee. The recommendation to stop the study was not based on any safe...

Eligibility Criteria

Inclusion

  • Adult male and female subjects with primary DSM-IV diagnosis of GAD, as confirmed by the MINI structured interview.
  • Historical failure to respond optimally to a GAD treatment

Exclusion

  • Current primary DSM-IV (Diagnostic and Statistical Manual of Mental Disorders 4th edition) diagnosis of major depressive disorder with or without seasonal pattern, dysthmic disorder, depressive disorder NOS (not otherwise specified), social phobia, panic disorder with or without agoraphobia, post traumatic stress disorder, dissociative disorder, borderline personality disorder, obsessive-compulsive disorder, antisocial personality disorder, as defined in the DSM-IV TR (Diagnostic and Statistical Manual of Mental Disorders 4th edition, Text Revision).
  • Past and/or current DSM-IV diagnosis of schizophrenia, schizoaffective disorder, other psychotic disorders, bipolar disorders (I or II), factitious disorder or cognitive disorder (including delirium, dementia, and amnestic disorder).

Key Trial Info

Start Date :

December 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2008

Estimated Enrollment :

356 Patients enrolled

Trial Details

Trial ID

NCT00413010

Start Date

December 1 2006

End Date

March 1 2008

Last Update

February 10 2021

Active Locations (68)

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Page 1 of 17 (68 locations)

1

Pfizer Investigational Site

Arcadia, California, United States, 91007-3462

2

Pfizer Investigational Site

Burbank, California, United States, 91506

3

Pfizer Investigational Site

Redlands, California, United States, 92374

4

Pfizer Investigational Site

Sherman Oaks, California, United States, 91403