Status:

COMPLETED

Clinical Impact of Fluoroquinolone Resistance in Bacteremia Caused by Gram-Negative Bacilli of Urinary Tract Origin

Lead Sponsor:

University of Pittsburgh

Collaborating Sponsors:

Japan Health Sciences Foundation

Conditions:

Urinary Tract Infection

Fluoroquinolone

Eligibility:

All Genders

18+ years

Brief Summary

The information collected will optimize the management of patients with urinary tract infections with secondary bacteremia, primarily with gram negative bacteria especially Escherichia coli. The curre...

Detailed Description

The following information will be collected: age, sex, occupation, hospital location at the time of positive culture (ER, medical ward, ICU etc), prior hospitalization, receipt of outpatient dialysis,...

Eligibility Criteria

Inclusion

  • Clinical information is collected by chart review of "case" and "control" patients. A "case" patient is defined as follows:
  • One or more blood cultures are positive for Gram-negative bacteria.
  • The same organism is recovered in urine culture within a 48-hour period.
  • The organism is ciprofloxacin resistant.
  • A "control" patient is defined as follows:
  • One or more blood cultures are positive for Gram-negative bacteria.
  • The same organism is recovered in urine culture within a 48-hour period.
  • The organism is ciprofloxacin susceptible.

Exclusion

  • negative culture

Key Trial Info

Start Date :

February 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2017

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT00414362

Start Date

February 1 2007

End Date

June 1 2017

Last Update

June 12 2018

Active Locations (1)

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1

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15213