Status:
COMPLETED
Using Ultrasonography to Predict Clinical Response to Intraarticular Corticosteroids in Knee Osteoarthritis
Lead Sponsor:
University of California, San Diego
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
The primary purposes of this study are the following: 1. To evaluate whether the presence of inflammatory knee osteoarthritis as determined by ultrasonography can be used as a clinical predictor of p...
Detailed Description
Osteoarthritis (OA) has previously been thought to be a non-inflammatory condition whose pathologic hallmark is destruction of hyaline cartilage. It is now realized that OA results from a complex inte...
Eligibility Criteria
Inclusion
- Both male and female patients are eligible for the study if they are between 40 and 80 years old, have symptomatic knee OA requiring treatment, and have not responded adequately to treatment with acetominophen or NSAIDs.
Exclusion
- Severe OA as defined by radiographic Kellgren and Lawrence Grade IV
- The patient being wheel-chair bound
- Previous knee operation on the affected side within the past year or history of total knee arthroplasty (affected side)
- Any IA steroid or injections in the last 3 months or viscosupplementation in the last 6 months
- Local sepsis
- Local skin conditions
- Serious concomitant medical illness.
Key Trial Info
Start Date :
December 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2009
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00414427
Start Date
December 1 2005
End Date
June 1 2009
Last Update
July 8 2010
Active Locations (2)
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1
Thorton Hospital
La Jolla, California, United States, 92037
2
La Jolla Veterans Affairs Medical Center
San Diego, California, United States, 92161