Status:
TERMINATED
Pulmonary Rehabilitation in Patients With Fibrotic Interstitial Lung Disease
Lead Sponsor:
University of California, San Francisco
Conditions:
Fibrotic Interstitial Lung Disease
Eligibility:
All Genders
Phase:
NA
Brief Summary
Our study aims to investigate the benefits of an outpatient pulmonary rehabilitation program in a population of subjects with fibrotic interstitial lung disease. Our hypothesis is that pulmonary rehab...
Eligibility Criteria
Inclusion
- Restriction on pulmonary function testing (TLC \<80%, FEV1/FVC ratio \> predicted or DLCO \< 80%)
- Evidence of fibrosis on high resolution computed tomography of the chest.
- Fibrosis on surgical lung biopsy if performed
- Referral for pulmonary rehabilitation
Exclusion
- Participation in pulmonary rehabilitation in the past 24 months
- Inability to complete 6 minute walk test or study questionnaires
- Limitations other than dyspnea (e.g. arthritis) that affect ability to participate in pulmonary rehabilitation
- Baseline 6 minute walk distance \> 400 meters
- Planned change in medication treatment for lung disease during the course of pulmonary rehabilitation
- Ejection fraction known to be \< 25%
- Contraindications to pulmonary rehabilitation (clinically unstable, uncontrolled arrhythmia or hypertension, symptomatic or uncontrolled hypotension with systolic blood pressure of \< 95, active angina, unexplained syncope or worsening dizziness, limiting orthopedic or neurological disorders, psychiatric impairment that inhibits cooperation in the program)
- FEV1/FVC \< 65%
- Unable to provide informed consent
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
End Date :
July 1 2007
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00415272
End Date
July 1 2007
Last Update
January 15 2008
Active Locations (1)
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1
University of California at San Francisco
San Francisco, California, United States, 94123