Status:

COMPLETED

Safety and Tolerability of IC83/LY2603618 Administered After Pemetrexed 500 mg/m2 Every 21 Days in Patients With Cancer

Lead Sponsor:

Eli Lilly and Company

Conditions:

Cancer

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

The purpose of this study is to evaluate the safety and tolerability of IC83/LY2603618 for the treatment of cancer.

Eligibility Criteria

Inclusion

  • Has at least one lesion that can be evaluated by Response Evaluation Criteria In Solid Tumors (RECIST)
  • Has fully recovered from all toxicities due to the following:
  • Local radiation therapy that ended at least 14 days prior to Cycle 1, Day 1.
  • Surgery.
  • Has a life expectancy of at least 3 months.
  • Negative serum pregnancy test.

Exclusion

  • Is pregnant or breastfeeding.
  • Is a woman of childbearing potential unwilling to use an approved, effective means of contraception according to the institution's standards.
  • Is a man of childbearing potential unwilling to use an approved, effective means of contraception according to the institution's standards.
  • Has a history of brain metastases, unless adequately treated and without radiologic evidence of progressive disease for at least 3 months after completion of therapy.
  • Has a known active infection.

Key Trial Info

Start Date :

January 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2010

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT00415636

Start Date

January 1 2007

End Date

July 1 2010

Last Update

October 19 2018

Active Locations (1)

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Scottsdale, Arizona, United States, 85258