Status:

COMPLETED

Efficacy of Sublingual Midazolam in Association With Oral Morphine in Children Analgesia After Bone Fracture

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Collaborating Sponsors:

URC-CIC Paris Descartes Necker Cochin

Conditions:

Fractures

Eligibility:

All Genders

5-16 years

Phase:

PHASE3

Brief Summary

It is a randomized simple-blind monocentric study; the group A will receive oral morphine with placebo and the group B will receive oral morphine with sublingual midazolam. The aim of this study is to...

Detailed Description

Fracture is often responsible of pain in the paediatric emergency department (ED). This pain is very severe and needs effective drugs. During a study made at the ED of Necker Enfants Malades Hospital...

Eligibility Criteria

Inclusion

  • children between 5 and 16 years old
  • children with a disjoined bone fracture
  • children needed oral morphine analgesia
  • written informed consent from one or the two parents or legal pad

Exclusion

  • ASA score \> 2
  • concomitant administration of oral analgesia (level II WHO classification) less than 6 hours
  • concomitant administration of benzodiazepine less than 24 hours

Key Trial Info

Start Date :

January 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2009

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00416039

Start Date

January 1 2007

End Date

February 1 2009

Last Update

November 20 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hopital Necker enfants Malade - Department of Pediatric Emergency

Paris, France, 75015