Status:
COMPLETED
Is Dexmedetomidine Associated With a Lower Incidence of Postoperative Delirium When Compared to Propofol or Midazolam in Cardiac Surgery Patients
Lead Sponsor:
Stanford University
Collaborating Sponsors:
Abbott
Conditions:
Delirium
Eligibility:
All Genders
18-89 years
Brief Summary
The purpose of this chart review study is to determine whether the use of dexmedetomidine, a selective α2-adrenergic receptor agonist with sedative, analgesic, and antinociceptive properties, would be...
Detailed Description
Delirium is the most common psychiatric syndrome found in the general hospital setting. Between 32 - 80% of cardiac surgery patients may experience post-operative delirium. Because failure to recogniz...
Eligibility Criteria
Inclusion
- Diagnosis of a coronary artery disease, cardiac valve disease, or vascular problems requiring elective surgical intervention
- Age older than 18 years of age, less than 90 years of age
- Fluency in English, and willingness to participate in the study
- No history of recent (\< 3 months) of alcohol or drug abuse
- No pre-operative evidence of heart block
- No history of dementia, schizophrenia, or post-traumatic stress disorder
Exclusion
- A preexisting diagnoses of dementia, schizophrenia, active or recent alcohol or drug abuse/dependence; post-traumatic stress disorder; acute intoxication (i.e., positive urine drug and/or alcohol test at the time of initial evaluation or upon hospitalization for surgery)
- Age younger than 18, or older than 89 years of age
- Inability to understand enough English to complete required diagnostic testing
- Unwillingness to participate in the study
- Inability of subject or surrogate to consent.
- Pregnancy
Key Trial Info
Start Date :
April 1 2002
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2004
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00417664
Start Date
April 1 2002
End Date
April 1 2004
Last Update
May 27 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Stanford University Medical Center
Stanford, California, United States, 94305