Status:

COMPLETED

Phase III Study to Assess the Long Term Efficacy, Carry-over Effect and Safety of 300 IR Sublingual Immunotherapy Tablets

Lead Sponsor:

Stallergenes Greer

Conditions:

Allergy

Eligibility:

All Genders

18-50 years

Phase:

PHASE3

Brief Summary

A phase III study to evaluate Long term efficacy , carry-over effect and safety of 300 IR sublingual Immunotherapy (SLIT) tablets in adults patients suffering from grass pollen rhinoconjunctivitis

Eligibility Criteria

Inclusion

  • Male or female outpatients aged 18 to 50 years
  • Grass pollen-related allergic rhinoconjunctivitis for at least the last two pollen seasons
  • Positive SPT and specific IgE values of at least Class 2 for grass pollen allergens
  • A score of greater than or equal to 12 out of a possible 18 on the Retrospective Rhinoconjunctivitis Total Symptom Score (RRTSS)

Exclusion

  • Patients with symptoms of rhinoconjunctivitis during the grass pollen season due to sensitisation to allergens other than grass pollen must not be included. Patients must be asymptomatic to all other allergens during the grass pollen season. Patients who have allergic rhinitis due to perennial allergen may not be included.
  • Asthma requiring treatment other than beta-2 inhaled agonists.
  • Patients who have received any desensitisation treatment for grass pollen or with any other allergen within the previous 5 years.

Key Trial Info

Start Date :

December 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2011

Estimated Enrollment :

633 Patients enrolled

Trial Details

Trial ID

NCT00418379

Start Date

December 1 2006

End Date

September 1 2011

Last Update

May 25 2016

Active Locations (1)

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1

DIDIER

Toulouse, France, 31400