Status:

COMPLETED

Treatment of Schizophrenia With an Omega-3 Fatty Acid (EPA) and Antioxidants

Lead Sponsor:

University Hospital, Aker

Collaborating Sponsors:

Diakonhjemmet Hospital

Stanley Medical Research Institute

Conditions:

Schizophrenia

Schizophreniform Disorders

Eligibility:

All Genders

18-40 years

Phase:

PHASE2

PHASE3

Brief Summary

The purpose of this trial is to study the effect of adding the omega-3 fatty acid EPA and/or Vitamins E + C to antipsychotic drugs in younger patients with schizophrenia and related psychoses.

Detailed Description

Objective: Study the effect of adding Ethyl-EPA and/or Vitamins E + C to antipsychotic drugs in younger patients with schizophrenia and related psychoses. Methods and material: * Design: Multicentr...

Eligibility Criteria

Inclusion

  • Patients with schizophrenia, schizophreniform disorder or schizoaffective disorder (DSM-IV)
  • Admitted to a psychiatric hospital/department within the previous twenty-one days before screening
  • Less than fifteen years, in retrospect, since first psychotic symptoms (DSM-IV 295, criteria A,1-4)
  • Age 18-40 years
  • Speaks fluently a Scandinavian language
  • A written informed consent must be obtained before any trial-related activities

Exclusion

  • A diagnosis of substance dependence (DSM-IV)
  • Known allergy to study medication
  • Currently taking warfarin or having anamnestic indicators of impaired haemostasis (profuse bleeding, except epistaxis)

Key Trial Info

Start Date :

September 1 2001

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2004

Estimated Enrollment :

99 Patients enrolled

Trial Details

Trial ID

NCT00419146

Start Date

September 1 2001

End Date

April 1 2004

Last Update

January 4 2011

Active Locations (1)

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1

Aker University Hospital

Oslo, Norway, 0320